Upton joins from The Scottish Malt Whisky Society where he specialised in offering personalised tastings for high-value clients.
He is one of the youngest members of The Scottish Malt Whisky Society tasting panel, as well as working in the Royal Lochnagar distillery and providing consultant and tasting services to independent bottlers.
Upton will represent Distell globally for its single malts portfolio, which includes Bunnahabhain, Deanston, Ledaig and Tobermory.
Distell Malts global marketing manager Alison Gibb said: “Angus’ enthusiasm and category expertise is clear to see and will be invaluable as he represents our unique brands in key global markets.
Upton said: “Joining such an established whisky producer has been a long-term ambition of mine and I’m honoured to join the team.